Lambda Light Chain Antibody

• Catalog Number: orb2636421
• Category: Antibodies
• Description: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
• Clonality: Recombinant
• Species/Host: Rabbit
• Isotype: Rabbit IgG, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: Recombinant full-length human Lambda light chain protein was used as the immunogen for the recombinant IGL antibody.
• UniProt ID: P01842, P01701
• Tested applications: ELISA
• Dilution range: ELISA
• Application notes: Optimal dilution of the recombinant IGL antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: IGL/3886R
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This recombinant IGL antibody is available for research use only.
• Note: For research use only