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Catalog Number | orb181270 |
---|---|
Category | Small Molecules |
Description | kobe2602 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM. |
CAS Number | [454453-49-7] |
MW | 419.31096 |
SMILES | FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(F)C=C2)=S)C([N+]([O-])=O)=C1)(F)F |
Formula | C14H9N5O4F4S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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