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    KMT6 Antibody

    KMT6 Antibody

    Catalog Number: orb1730416

    DispatchUsually dispatched within 5-10 working days
    $ 296.00
    Catalog Numberorb1730416
    CategoryAntibodies
    DescriptionPolycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
    Species/HostRabbit
    ClonalityPolyclonal
    Tested applicationsFC, ICC, IHC, WB
    ReactivityHuman, Mouse, Rat
    IsotypeRabbit IgG
    ImmunogenA synthesized peptide derived from human KMT6 / EZH2
    Dilution rangeWB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200; RCM: 1/50-1/100
    ConjugationUnconjugated
    MWCalculated MW: 85 kDa; Observed MW: 98 kDa
    Entrez2146
    UniProt IDQ15910
    StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Buffer/PreservativesRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Alternative namesWVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2
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    NoteFor research use only
    Expiration Date12 months from date of receipt.
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