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Catalog Number | orb303199 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal antibody to KLK5 |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Predicted Reactivity | Human |
Reactivity | Human |
Immunogen | KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337 |
Dilution range | WB: 1: 1000 |
Form/Appearance | Lyophilized |
Purity | Serum |
Conjugation | Unconjugated |
MW | 32 | 37 kDa |
UniProt ID | Q9Y337 |
Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
Note | For research use only |
Application notes | Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2 |
Expiration Date | 12 months from date of receipt. |
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