KDM7 antibody

• Catalog Number: orb67003
• Category: Antibodies
• Description: Rabbit polyclonal to KDM7.Lysine-specific histone demethylase 7 (KDM7) is a histone demethylase required for braindevelopment. KDM7 specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 andH3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue(H4K20Me1), thereby playing a central role in histone code. KDM7 specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3,it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human KDM7
• Dilution range: WB:1:500-1:1000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 107
• UniProt ID: Q6ZMT4
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-KDM7 antibody,anti-Lysinespecific demethylase
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using KDM7 antibody