KDM2A antibody

• Catalog Number: orb67176
• Category: Antibodies
• Description: Rabbit polyclonal to KDM2A.Lysine-specific demethylase 2A (KDM2A) is a histone demethylase belonging to the JHDM1 histonedemethylase family. KDM2A specifically demethylates 'Lys-36' of histone H3, thereby playing acentral role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while ithas weak or no activity for mono-and tri-methylated H3 'Lys-36'. KDM2A is required to maintain theheterochromatic state. It associates with centromeres and represses transcription of small non-codingRNAs encoded by the clusters of satellite repeats at the centromere. KDM2A is required to sustaincentromeric integrity and genomic stability, particularly during mitosis.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human KDM2A
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 133
• UniProt ID: Q9Y2K7
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-KDM2A antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane) and human Jurkat(Lane2) using KDM2A antibody