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Catalog Number | orb66924 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to KAISO.KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulatorwith bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in theconsensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation andthe formation of repressive chromatin structures in target gene promoters. In contrast, KAISO mayalso activate transcription of a subset of target genes by the recruient of CTNND2. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human, Mouse |
Immunogen | N-terminal region of mouse KAISO |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 74 |
UniProt ID | Q8BN78 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-KAISO antibody,anti-ZBTB33 antibody,anti-ZNF3 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot of total cell extracts from human MCF7, using Ab (orb66924) at RT for 2 h.
ELISA, IF, IHC-P, WB | |
Rat | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
ChIP, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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