Jun9-62-2R (dichloroacetamide)

• Catalog Number: orb1910957
• Category: Small Molecules
• Description: Jun9-62-2R (dichloroacetamide) is a selective covalent Mpro inhibitor with IC50 of 0.43 μM and viral replication with EC50 of 2.05 μM in Caco2-hACE2 cells. Jun9-62-2R (dichloroacetamide) is highly selective toward Mpro and does not inhibit the host calpain I, cathepsins B, K, L, caspase-3, and trypsin. The widely used antibiotic chloramphenicol contains the dichloroacetamide, suggesting Jun9-62-2R might be tolerated in vivo.
• MW: 518.44
• SMILES: O=C(N[C@@H](C1=CC=CC=C1)C)[C@@H](N(C(C(Cl)Cl)=O)C2=CC=C(C3=CC=CC=C3)C=C2)C4=CC=CN=C4
• Formula: C₂₉H₂₅Cl₂N₃O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.