JNJ-63576253 (TRC-253)

• Catalog Number: orb1089649
• Category: Small Molecules
• Description: JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.
• CAS Number: [2110426-27-0]
• MW: 502.516
• SMILES: C(F)(F)(C1=CC(N2C(N(C3C=CC(=NC=3)OC3CCNCC3)C3(CCC3)C2=O)=S)=CN=C1C#N)F
• Formula: C₂₃H₂₁F₃N₆O₂S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.