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JAK3-IN-1

JAK3-IN-1

Catalog Number: orb1707165

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Catalog Numberorb1707165
CategorySmall Molecules
DescriptionJAK3-IN-1
CAS Number1805787-93-2
Purity98.00%
MW508.02
SMILESO=C(C=C)NC1=CC=CC(=C1)CNC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCN(C)CC4
FormulaC26H30ClN7O2
Biological ActivityJAK3-IN-1 is a selective and orally active JAK3 inhibitor (IC50: 4.8 nM). JAK3-IN-1 displays over 180-fold more selective for JAK3 than JAK1 (IC50: 896 nM) and JAK2 (IC50: 1050 nM).
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • JAK3-IN-1 [orb611792]

    [1805787-93-2]

    508.0151

    C26H30ClN7O2

    100 mg, 10 mg, 50 mg