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Catalog Number | orb1709375 |
---|---|
Category | Small Molecules |
Description | JAK2/FLT3-IN-1 |
CAS Number | 2387765-27-5 |
Purity | 98% |
MW | 467.58 |
SMILES | CC=1C(C2=CN(C(C)C)N=C2)=NC(NC3=CC(F)=C(C=C3)N4CCC(N(CCO)C)CC4)=NC1 |
Formula | C25H34FN7O |
Biological Activity | JAK2/FLT3-IN-1 has anti-cancer activity. JAK2/FLT3-IN-1 is a potent and orally effective dual JAK2/FLT3 (Janus kinase 2/ FMS-like tyrosine kinase 3) inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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