Interferon alpha 1 Antibody / IFNA1

• Catalog Number: orb749586
• Category: Antibodies
• Description: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 2.52
• Tested applications: ELISA
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.
• Antibody Type: Primary Antibody
• Dilution range: ELISA (order the BSA-free format for coating)
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This Interferon alpha antibody is available for research use only.
• UniProt ID: P01562
• Storage: Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the Interferon alpha antibody should be determined by the researcher.1. This clone is also referred to as clone 2-52.
• Expiration Date: 12 months from date of receipt.

SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha Antibody (clone 2.52). Confirmation of Integrity and Purity of the Antibody.