Integrin-Linked Kinase (ILK)

• Catalog Number: RCP9299
• Category: Proteins
• Description: Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage-independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• MW: 55.92 kDa
• UniProt ID: Q13418
• Protein Length: Met1- Lys452
• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Storage: at -20 °C
• Buffer/Preservatives: 25 mM Sodium acetate pH 4.8, 50 % Glycerol
• Alternative names: ILK-1, ILK-2, 59 kDa serine/threonine-protein kina
• Note: For research use only
• Application notes: ELISA, Western Blotting, etc.
• Expiration Date: 6 months from date of receipt.