Integrin alpha 4 Antibody

• Catalog Number: orb1906355
• Category: Antibodies
• Description: Integrin alpha 4 Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: HP1/2
• Tested applications: Blocking, FA, FC, IP
• Reactivity: Guinea pig, Human
• Isotype: IgG1
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: Integrin alpha 4
• UniProt ID: P13612
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: CD49d; VLA-4; α4; VLA4; ITGA4; α4β1; α4 integrin;
• Note: For research use only
• Application notes: This antibody can be used for the immunoprecipitation of VLA-4 from cell lysates (PMID: 2430809). This antibody is also capable of detecting integrin alpha 4 expressed on the surface of Ramos cells by flow cytometry (PMID: 2430809; 1689216). This antibody can also block adherence of CTT leukocytes to recombinant soluble VCAM 1-coated plates in vitro (PMID: 7686922). This antibody can also block the interaction of VLA-4 with fibronectin. This antibody does not cause cell aggregation (PMID: 1709929). This antibody can bind soluble integrin alpha-4 in an ELISA. This antibody also inhibited the binding of PAF-stimulated eosinophils to MAdCAM-1 transfectants. This antibody also inhibited binding of unstimulated eosinophils to soluble recombinant human (rh)VCAM-1 and fibronectin (Fn) (PMID: 8911148).
• Expiration Date: 12 months from date of receipt.