INSR antibody

• Catalog Number: orb379724
• Category: Antibodies
• Description: Goat polyclonal antibody to insulin receptor. INSR is a receptor tyrosine kinase. Preprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. The insulin signalling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein is activated by the binding of insulin or other ligands to this receptor.
• Species/Host: Goat
• Clonality: Polyclonal
• Tested applications: IHC-Fr, IHC-P, WB
• Reactivity: Bovine, Canine, Donkey, Equine, Feline, Gallus, Goat, Guinea pig, Hamster, Human, Mouse, Other, Porcine, Primate, Rabbit, Rat, Sheep
• Isotype: IgG
• Immunogen: Purified recombinant peptide within residues 1310 aa to the C-terminus of human INSR produced in E. coli.
• Concentration: 3 mg/ml
• Dilution range: WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
• Form/Appearance: Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
• Conjugation: Unconjugated
• Target: INSR
• Storage: Store at -20°C for long-term storage. Store at 2-8°C for up to one month.
• Buffer/Preservatives: PBS, 20% glycerol and 0.05% sodium azide
• Alternative names: CD220, HHF5, insulin receptor antibody.
• Note: For research use only
• Application notes: The antibody solution should be gently mixed before use.
• Expiration Date: 12 months from date of receipt.

Western blot analysis of human recombinant protein using INSR antibody