Infigratinib Phosphate

• Catalog Number: orb864226
• Category: Small Molecules
• Description: NVP-BGJ398 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic and antirachitic activities. NVP-BGJ398 inhibits cell viability in colon cancer cells and prevents progression and tumor formation in animal models of malignant rhabdoid tumors. In endometrial cancer cells, NVP-BGJ398 induces cell cycle arrest and inhibits growth; in vivo, it also inhibits tumor growth. NVP-BGJ398 inhibits aberrant FGFR signaling in animal models of rickets disease, normalizing bone growth and mineralization.
• CAS Number: 1310746-10-1
• Purity: ≥98%
• MW: 658.5
• SMILES: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl.OP(=O)(O)O
• Hazard Information: Non-Toxic
• Storage: Storage Temp: -20°C
• Alternative names: NVP-BGJ398 Phosphate, BGJ-398 phosphate
• Note: For research use only
• Expiration Date: 12 months from date of receipt.