(Z)-Ligustilide

SKU: orb1707974

Description

(Z)-Ligustilide, a bioactive phthalide from Angelica and Cnidium species, suppresses benzo(a)pyrene-induced CYP1A1 expression in human keratinocytes by activating the Nrf2 pathway via reactive oxygen species (ROS). This mechanism highlights its application in researching chemoprevention, oxidative stress, and detoxification pathways in skin models.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 81944-09-4
• MW: 190.24
• Purity: 98.81%
• Formula: C₁₂H₁₄O₂
• SMILES: CCC/C=C\1/C2=C(C=CCC2)C(=O)O1
• Target: Antibacterial,Estrogen Receptor/ERR
• Solubility: DMSO:100 mg/mL (525.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (21.03 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, bacterial, (Z) Ligustilide, (Z)Ligustilide, (Z)-Ligustilide, cis-Ligustilide, Inhibitor, Ligustilide, Ligustilide A, inhibit

Compound Identifiers

PubChem CID

5319022