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UNC6852
Catalog Number: orb746512
| Catalog Number | orb746512 |
|---|---|
| Category | Small Molecules |
| Description | UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED. |
| MW | 832.969627380371 |
| Formula | C43H48N10O6S |
| SMILES | O=C(NCCCC(=O)N[C@@H](C(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(C2SC=NC=2C)=CC=1)C1C=CC(C2C3=NN=CN3C(NCC3OC=CC=3)=NC=2)=CC=1 |
| Note | For research use only |
UNC6852 [orb1940743]
> 98% (HPLC)
2688842-08-0
394.4
C22H22N2O5
500 mg, 200 mg, 10 mg, 25 mg, 50 mg, 100 mg, 5 mg, 1 gUNC6852 [orb1308745]
≥98%
2688842-08-0
832.97
C43H48N10O6S
50 mg, 100 mg, 1 mg, 5 mg, 10 mg, 25 mg, 1 ml x 10 mM (in DMSO)(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base) [orb1987762]
98.00%
629.69
C28H38F3N5O6S
500 mg, 100 mg
