(S,R,S)-AHPC-C3-NH2

• Catalog Number: orb1987761
• Category: Small Molecules
• Description: (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate comprising an E3 ligase ligand-linker and a VH032-based VHL ligand, commonly used in PROTAC technology. This compound is essential in synthesizing various PROTACs, such as UNC6852, a bivalent chemical degrader that specifically targets EED [1].
• Purity: 98.00%
• MW: 515.67
• Biological Activity: (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component in the synthesis of various PROTACs, including UNC6852. UNC6852 is a bivalent chemical degrader specifically targeting EED [1].
• CAS Number: [2361119-88-0]
• Formula: C₂₆H₃₇N₅O₄S
• SMILES: C([C@@H](NC(CCCN)=O)[C@@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• Storage: -20°C
• Note: For research use only