Ponatinib-d8

SKU: orb1991547

Description

Ponatinib D8 is a deuterated analog of the multi-kinase inhibitor Ponatinib. This compound potently inhibits targets including Abl, PDGFRα, VEGFR2, FGFR1, and Src, and is widely used as an internal standard in LC-MS for pharmacokinetic studies in both in vitro and in vivo cancer research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1562993-37-6
• MW: 540.61
• Formula: C₂₉H₂₇F₃N₆O
• SMILES: [2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)C1([2H])[2H]
• Target: Src,Bcr-Abl,FGFR,VEGFR,PDGFR,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73214034