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NR2F1 agonist 1

NR2F1 agonist 1

Catalog Number: orb1744674

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Catalog Numberorb1744674
CategorySmall Molecules
DescriptionNR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model.
Purity98.00%
MW470.63
Biological ActivityNR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model.
CAS Number374101-64-1
FormulaC28H30N4OS
SMILESCCSC1=NN=C2N1C1=C(C(=O)N2CCC2=CC=CC=C2)C2(CCCCC2)CC2=C1C=CC=C2
Storage-20°C
NoteFor research use only