MC-VC-PABC-C6-alpha-Amanitin

SKU: orb1942934

Description

MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate (ADC) designed for targeted delivery of the RNA polymerase II inhibitor alpha-Amanitin to HER2-positive cells. It serves as a key research tool for investigating targeted therapies in HER2-overexpressing cancers, such as breast and gastric cancer, in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 2922514-69-8
• MW: 1616.79
• Formula: C₇₄H₁₀₅N₁₇O₂₂S
• SMILES: O=S1C2=C(C=3C(N2)=CC(OCCCCCCNC(OCC4=CC=C(NC([C@H](NC([C@H](NC(CCCCCN5C(=O)C=CC5=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C4)=O)=CC3)C[C@@]6(NC(=O)[C@]([C@H]([C@H](CO)O)C)(NC(=O)[C@]7(N(C(=O)[C@H](CC(N)=O)NC(=O)[C@](C1)(NC(=O)CNC(=O)[C@]([C@H](CC)C)(NC(=O)CNC6=O)[H])[H])C[C@H](O)C7)[H])[H])[H]
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176418795