Fmoc-L-Asn(EDA-N3)-OH

SKU: orb2663839

Description

Fmoc-L-Asn(EDA-N3)-OH is a chemical compound equipped with an azide group used in click chemistry. Reports in the literature have demonstrated its application in the modification of α-amanitin, the deadliest member of the amatoxin peptide family produced by the death cap mushroom. α-Amanitin is a highly lethal natural compound (LD50=50-100 µg/kg), an orally ingested rigid bicyclic octapeptide, acting as a highly selective conformational inhibitor of RNA polymerase II.

Key Properties

• CAS Number: 2616562-74-2
• MW: 423.42
• Formula: C₂₁H₂₁N₅O₅
• SMILES: C(OC(N[C@@H](CC(NCCN=[N+]=[N-])=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
• Target: ADC Linker

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ADC Linker