DN-108

SKU: orb3027687

Description

DN-108, a thiazolidinedione derivative, acts as an orally active peroxisome proliferator-activated receptor γ (PPARγ) agonist with antidiabetic properties. It improves hyperglycemia, hypertriglyceridemia, and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increases 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity, making it a promising candidate for type 2 diabetes research.

Key Properties

• CAS Number: 195604-21-8
• MW: 366.43
• Formula: C₂₀H₁₈N₂O₃S
• SMILES: O=C1SC(C(=O)N1)CC2=CC=C(C=C2)NC(=O)C3(C=4C=CC=CC4)CC3
• Target: PPAR

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PPAR