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Dehydrocorydaline
Catalog Number: orb1301239
| Catalog Number | orb1301239 |
|---|---|
| Category | Small Molecules |
| Description | Dehydrocorydaline |
| CAS Number | 30045-16-0 |
| Purity | 99.84% |
| MW | 366.43 |
| SMILES | CC1=C2C=3C(=CC(OC)=C(OC)C3)CC[N+]2=CC=4C1=CC=C(OC)C4OC |
| Formula | C22H24NO4 |
| Biological Activity | 1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Dehydrocorydaline chloride [orb1309778]
99.88%
10605-03-5
401.88
C22H24ClNO4
25 mg, 1 ml x 10 mm (in DMSO), 100 mg, 1 mg, 5 mg, 10 mg, 50 mgDehydrocorydaline nitrate [orb1304637]
99.79%
13005-09-9
428.44
C22H24N2O7
1 ml x 10 mm (in DMSO), 25 mg, 50 mg, 5 mg, 1 mg, 10 mg
