Bisdemethoxycurcumin

SKU: orb1297660

Description

Bisdemethoxycurcumin (Curcumin III) is a stable curcumin derivative that enhances macrophage phagocytosis, particularly in amyloid-β clearance research. It exhibits anticancer properties by suppressing proliferation via p300/Wnt/β-catenin pathway inhibition and modulates inflammation by reducing LPS-induced iNOS expression in vitro.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 24939-16-0
• MW: 308.33
• Purity: 99.75% (May vary between batches)
• Formula: C₁₉H₁₆O₄
• SMILES: Oc1ccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)cc1
• Target: Wnt/beta-catenin,DNA/RNA Synthesis,Ferroptosis,Epigenetic Reader Domain,P-gp
• Solubility: Ethanol:5 mg/mL (16.22 mM);DMSO:67 mg/mL (217.3 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antioxidant, antiinflammatory, bcatenin, Bisdemethoxycucurmin, Bisdemethoxycurcumin, betacatenin, beta-catenin, Curcumin III, curcuminoid, Didemethoxycurcumin, inhibit, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain, βcatenin, Wnt, Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, p300

Compound Identifiers

PubChem CID

5315472