Antitumor agent-81

• Catalog Number: orb1744829
• Category: Small Molecules
• Description: Antitumor agent-81, a P62-RNF168 agonist with low cytotoxicity, enhances the P62-RNF168 interaction, leading to decreased RNF168-mediated H2A ubiquitination and impaired homologous recombination-mediated DNA repair. Additionally, it exhibits dose-dependent inhibition of xenograft tumor growth in mice.
• Purity: 98.00%
• MW: 393.4
• Biological Activity: Antitumor agent-81, a P62-RNF168 agonist with low cytotoxicity, enhances the P62-RNF168 interaction, leading to decreased RNF168-mediated H2A ubiquitination and impaired homologous recombination-mediated DNA repair. Additionally, it exhibits dose-dependent inhibition of xenograft tumor growth in mice.
• CAS Number: 2765180-17-2
• Formula: C₁₉H₁₉N₇O₃
• SMILES: O(C)C=1C=C(N2C=C(N=N2)C3=CC4=C(C=C3)N=C(N)N=C4N)C=C(OC)C1OC
• Storage: -20°C
• Note: For research use only