IL6ST Antibody

SKU: orb1410118

Description

Mouse monoclonal antibody to IL6ST

Research Area

Cardiovascular Research, Immunology & Inflammation, Neuroscience, Signal Transduction

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: IL6ST/4101
• Immunogen: Recombinant fragment of human IL6ST protein corresponding to extracellular domain(exact sequence is proprietary)
• Target: IL6ST
• Source/Expression System: Bioreactor
• Molecular Weight: 103kDa
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD130 antigen; CDw130; GP130 RAPS; IL-6RB; IL6ST; Interleukin 6 receptor subunit beta; Interleukin receptor beta chain; Interleukin-6 signal transducer; Membrane glycoprotein 130; Oncostatin-M receptor subunit alpha

Analysis of Protein Array containing more than 19000 full-length human proteins using IL6RB / IL6ST Monospecific Mouse Monoclonal Antibody (IL6ST/4101). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human adrenal gland stained with IL6RB / CD130 Mouse Monoclonal Antibody (IL6ST/4101). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Quick Database Links

Gene Symbol

IL6ST

UniProt

P40189