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IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)

IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)

Catalog Number: orb1960598

DispatchUsually dispatched within 5-10 working days
$ 590.00
Catalog Numberorb1960598
CategoryProteins
DescriptionThe multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
TagC-His-Avi
Purity98.00%
MW41.4 kDa (predicted). Due to glycosylation, the protein migrates to 65-78 kDa based on Tris-Bis PAGE result.
UniProt IDP08887
Expression SystemHEK293 Cells
Biological OriginHuman
Biological ActivityThe multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Expression RegionLeu20-Pro365
Storage-20°C
NoteFor research use only
Application notesReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Expiration Date6 months from date of receipt.