IL-33 Protein, Rhesus macaque, Recombinant (His)

• Catalog Number: orb1961676
• Category: Small Molecules
• Description: IL-33 Protein, Rhesus macaque, Recombinant (His)
• Purity: 98.00%
• MW: 21 KDa, reducing conditions
• Biological Activity: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.