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Catalog Number | orb1960544 |
---|---|
Category | Small Molecules |
Description | IFNAR1 Protein, Mouse, Recombinant (hFc) |
Purity | 98.00% |
MW | The protein has a predicted MW of 72.5 kDa. Due to glycosylation, the protein migrates to 83-110 kDa based on Tris-Bis PAGE result. |
Biological Activity | IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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