Human uPAR / PLAUR Protein

• Catalog Number: orb257913
• Category: Proteins
• Description: Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
• Reactivity: Human
• Tag: C-7×His
• Form/Appearance: Powder
• Purity: 92%
• Conjugation: Unconjugated
• MW: 32.3 kDa
• Target: uPAR
• Protein Sequence: AAH02788
• Source: Human uPAR, His Tag (orb257913) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # AAH02788).
• Expression System: HEK293
• Expression Region: Leu 23 - Arg 303
• Endotoxins: 1.0 EU per μg
• NCBI: AAH02788
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: uPAR,PLAUR,CD87,MO3
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.3 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human uPAR protein