Human UBC7 protein

• Catalog Number: orb107814
• Category: Proteins
• Description: Human Ubquitin Conjugating Enzyme E2 L3 (UBE2L3)/UBCH7 is a class I enzyme which functions in the stress response andthe control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle.UBCH7 mediates the selective degradation of short-lived and abnormal proteins and is highly homologous to UBCH5. It hasbeen demonstrated to participate in the ubiquitinylation of p53, c-Fos and NFkB. UBCH7 is one of two E2s (UBCH5 being theother) with which HECT domain proteins interact with UBCH7 being able to efficiently substitute for UBCH5 in E6-APdependentubiquitinylation.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 95% by SDS-PAGE and HPLC analyses.
• Conjugation: Unconjugated
• MW: 18.9 kDa,
• Target: UBC7
• Protein Sequence: MHHHHHHAMA ASRRLMKELE EIRKCGMKNF RNIQVDEANL LTWQGLIVPDNPPYDKGAFR IEINFPAEYP FKPPKITFKT KIYHPNIDEK GQVCLPVISA ENWKPATKTDQVIQSLIALV NDPQPEHPLR ADLAEEYSKD RKKFCKNAEE FTKKYGEKRP VD
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, 1mM DTT, pH 7.5
• Alternative names: Human Ubquitin Conjugating Enzyme E2 L3/UBCH7 prot
• Note: For research use only
• Expiration Date: 6 months from date of receipt.