You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb257719 |
---|---|
Category | Proteins |
Description | Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. |
Reactivity | Human |
Tag | C-6×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 45.2 kDa |
Target | TrkB |
Protein Sequence | AAH31835 |
Source | Human TrkB, His Tag (orb257719) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - His 430 (Accession # AAH31835). |
Expression System | HEK293 |
Expression Region | Cys 32 - His 430 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH31835 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | NTRK2,TRKB,GP145-TrkB Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.2 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human TrkB protein
Unconjugated | |
98% | |
70.4 kDa | |
Human TrkB, Fc Tag (orb257720) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - His 430 (Accession # AAH31835). |
Filter by Rating