Human Siglec-5 / CD170 Protein

• Catalog Number: orb257840
• Category: Proteins
• Description: Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 73.0 kDa
• Target: Siglec-5
• Protein Sequence: AAH29896
• Source: Human Siglec-5, Fc Tag (orb257840) is expressed from human 293 cells (HEK293). It contains AA Glu 17 - Thr 434 (Accession # AAH29896).
• Expression System: HEK293
• Expression Region: Glu 17 - Thr 434
• Endotoxins: 1.0 EU per μg
• NCBI: AAH29896
• Storage: -20℃
• Buffer/Preservatives: Tris with Glycine, Arginine and NaCl, pH7.5
• Alternative names: SIGLEC5,OB-BP2,CD170,CD33L2
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.0 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Siglec-5 protein