Human Serpin G1 / C1 inhibitor Protein, His Tag (active enzyme, MALS verified)

• Catalog Number: orb1743042
• Category: Proteins
• Description: Serpin G1/C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in the blood is proportional to the level of the in vivo activation of these four cascade-like plasma enzyme systems. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE).
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 54.7 kDa
• Target: Serpin G1
• Source: Human Serpin G1 Protein, His Tag (orb1743042) is expressed from human 293 cells (HEK293). It contains AA Asn 23 - Ala 500 (Accession # P05155-1).
• Expression System: HEK293
• Expression Region: Asn 23 - Ala 500
• Endotoxins: 0.1 EU per μg
• Storage: -20°C
• Buffer/Preservatives: PBS, pH 7.4
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 54.7 kDa. The protein migrates as 75-105 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.