Human PTK7 / CCK4 Protein

• Catalog Number: orb750342
• Category: Proteins
• Description: PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 76.5 kDa
• Target: PTK7
• Protein Sequence: NP_002812.2
• Source: Human PTK7, His Tag (orb750342) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Thr 704 (Accession # Q13308-1).
• Expression System: HEK293
• Expression Region: Ala 31 - Thr 704
• Endotoxins: 1.0 EU per μg
• NCBI: NP_002812.2
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Pro
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Flow cytometric analysis of Human PTK7 protein.

SDS-PAGE analysis of Human PTK7 protein.