Human PTH1R / PTHR1 Protein

Catalog Number: orb257788

Catalog Number	orb257788
Category	Proteins
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor is also known as Parathyroid hormone 1 receptor (PTH1R), PTHR1, PTH/PTHrP type I receptor (PTH/PTHr receptor), which belongs to the G-protein coupled receptor 2 family. PTH1R / PTHR1 is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Reactivity	Human
Tag	C-7×His
Form/Appearance	Powder
Purity	85%
Conjugation	Unconjugated
MW	19.6 kDa
Target	PTH1R
Protein Sequence	NP_000307.1
Source	Human PTH1R, His Tag (orb257788) is expressed from human 293 cells (HEK293). It contains AA Asp 27 - Gly 188 (Accession # Q03431-1).
Expression System	HEK293
Expression Region	Asp 27 - Gly 188
Endotoxins	1.0 EU per μg
NCBI	NP_000307.1
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	PTH1R,PTHR,PTHR1 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.6 kDa. The protein migrates as 27-43 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human PTH protein

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human PTH1R(Tyr23-Met189) was fused with the C-terminal His Tag and expressed in Mammalian cells.