Human PROCR / EPCR / CD201 Protein

• Catalog Number: orb257784
• Category: Proteins
• Description: Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 48.6 kDa
• Target: PROCR
• Protein Sequence: AAH14451
• Source: Human PROCR, Fc Tag (orb257784) is expressed from human 293 cells (HEK293). It contains AA Ser 18 - Thr 209 (Accession # AAH14451).
• Expression System: HEK293
• Expression Region: Ser 18 - Thr 209
• Endotoxins: 1.0 EU per μg
• NCBI: AAH14451
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, pH7.5
• Alternative names: PROCR,EPCR,CD201,APC receptor,CCCA,CCD41
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human PROCR protein