Human PLGF / PGF Protein

• Catalog Number: orb257774
• Category: Proteins
• Description: Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 18.2 kDa
• Target: PLGF
• Protein Sequence: NP_002623.2
• Source: Human PLGF, His Tag (orb257774) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Arg 170 (Accession # NP_002623.2).
• Expression System: HEK293
• Expression Region: Leu 19 - Arg 170
• Endotoxins: 1.0 EU per μg
• NCBI: NP_002623.2
• Storage: -20℃
• Buffer/Preservatives: 100 mM Acetic Acid, pH3.0
• Alternative names: PGF,PLGF,PlGF,PGFL,SHGC-10760
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.2 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human PLGF protein