Human NPR1 / NPRA Protein

• Catalog Number: orb1176551
• Category: Proteins
• Description: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 75.3 kDa
• Target: NPR1
• Protein Sequence: NP_000897.3
• Source: Human NPR1, Fc Tag (orb1176551) is expressed from human 293 cells (HEK293). It contains AA Gly 33 - Glu 473 (Accession # P16066-1).
• Expression System: HEK293
• Expression Region: Gly 33 - Glu 473
• Endotoxins: 1.0 EU per μg
• NCBI: NP_000897.3
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Alternative names: Atrial natriuretic peptide receptor 1,NPR1,NPRA,GC
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.3 kDa. The protein migrates as 95-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.