Human NKp46 / NCR1 / CD335 Protein, Fc Tag

• Catalog Number: orb1806469
• Category: Proteins
• Description: Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 36.4 kDa
• Target: NKp46
• Source: Human NKp46 Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Thr 118 (Accession # O76036-1).
• Expression System: HEK293
• Expression Region: Glu 34 - Thr 118
• Endotoxins: 1.0 EU per μg
• Storage: -20°C
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.