Human Neutrophil defensin 1 / DEFA1 protein

• Catalog Number: orb1087558
• Category: Proteins
• Description: Human defensins are a family of small antimicrobial proteins found predominantly in leukocytes and epithelial cells that play important roles in the innate and adaptive immune defense against microbial infection. The α-defensins, human neutrophil peptides (HNPs) 1–3, are constitutively expressed in neutrophils and are the most abundant neutrophil granule proteins.
• Reactivity: Human
• Tag: C-Twin-Strep
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 9.8 kDa
• Target: Neutrophil defensin 1
• Protein Sequence: NP_004075.1
• Source: Human Neutrophil defensin 1, Twin-Strep Tag (orb1087558) is expressed from human 293 cells (HEK293). It contains AA Asp 39 - Cys 94 (Accession # P59665-1).
• Expression System: HEK293
• Expression Region: Asp 39 - Cys 94
• Endotoxins: 0.01 EU per μg
• NCBI: NP_004075.1
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Note: For research use only
• Application notes: This protein carries a twin strep tag at the C-terminus. The protein has a calculated MW of 9.8 kDa. The protein migrates as 11-14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.