Human MMP-8 Protein, His Tag (active enzyme) [Out of stock]

• Catalog Number: orb1742995
• Category: Proteins
• Description: Matrix metalloproteinase-8（MMP-8）also known as neutrophil collagenase and CLG1，is a member of matrix metalloproteinases (MMPs) family，which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Liquid
• Purity: 90%
• Conjugation: Unconjugated
• MW: 29.0 kDa
• Target: MMP-8
• Source: Human MMP-8 Protein, His Tag (orb1742995) is expressed from human 293 cells (HEK293). It contains AA Phe 21 - Gly 262 (Accession # P22894-1).
• Expression System: HEK293
• Expression Region: Phe 21 - Gly 262
• Endotoxins: 1.0 EU per μg
• Storage: -70°C
• Buffer/Preservatives: 50 mM Tris,150 mM NaCl,pH8.0
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.0 kDa. The protein migrates as 38-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.