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Catalog Number | orb257680 |
---|---|
Category | Proteins |
Description | Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 ,C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein,which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 28.7 kDa |
Target | LYPD3 |
Protein Sequence | AAH39167 |
Source | Human LYPD3, His Tag (orb257680) is expressed from human 293 cells (HEK293). It contains AA Leu 31 - His 286 (Accession # AAH39167). |
Expression System | HEK293 |
Expression Region | Leu 31 - His 286 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH39167 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | LYPD3,MIG-C4,C4.4A Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.7 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human LYPD3 protein
> 97% by SDS-PAGE. | |
KMP1329, Recombinant human LYPD3/C4.4A Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Leu31-His Tag286) of human LYPD3/C4.4A (Accession #NP_055215.2.) fused with a 6×His Tag at the C-terminus. |
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