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Human Lumican Protein
Catalog Number: orb257678
| Catalog Number | orb257678 |
|---|---|
| Category | Proteins |
| Description | Lumican (LUM) is also known as Keratan sulfate proteoglycan lumican, KSPG lumican,LDC and SLRR2D, which belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily. LUM /Lumican is present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage LUM /Lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. LUM participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of LUM has been correlated to the growth and metastasis of various malignancies. |
| Reactivity | Human |
| Tag | C-6×His |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 37.5 kDa |
| Target | Lumican |
| Protein Sequence | NP_002336 |
| Source | Human Lumican, His Tag (orb257678) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Asn 338 (Accession # NP_002336). |
| Expression System | HEK293 |
| Expression Region | Gln 19 - Asn 338 |
| Endotoxins | 1.0 EU per μg |
| NCBI | NP_002336 |
| Storage | -20℃ |
| Buffer/Preservatives | PBS, pH7.4 |
| Alternative names | LUM,Lumican,LDC,SLRR2D,KSPG lumican Read more... |
| Note | For research use only |
| Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.5 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human Lumican protein
Human LUM protein [orb392105]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Human cells
500 μg, 50 μg, 10 μgRecombinant Human Lumican/LUM Protein, His Tag [orb1550969]
> 95% by SDS-PAGE.
KMP1518, Recombinant Human Lumican/LUM Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Gln19-Asn338) of human Lumican/LUM (Accession #NP_002336.1) fused with a 6×His Tag at the C-terminus.
50 μg, 100 μgRecombinant Human Lumican/LUM Protein, His Tag [orb1552061]
≥90% as determined by SDS-PAGE
This protein contains the human LUM(Gln19-Asn338) was fused with the C-terminal His Tag and expressed in Mammalian cells.
50 μg, 100 μgHuman Lumican protein [orb754722]
ELISA, WB
Greater than 95% as determined by SDS-PAGE
35.5 kDa
E.Coli
100 μg, 1 mg, 200 μg, 50 μg
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