Human LRRC4 Protein

• Catalog Number: orb257675
• Category: Proteins
• Description: LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (G14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 92%
• Conjugation: Unconjugated
• MW: 55.8 kDa
• Target: LRRC4
• Protein Sequence: AAI11562.1
• Source: Human LRRC4, His Tag (orb257675) is expressed from human 293 cells (HEK293). It contains AA Ala 39 - Lys 527 (Accession # AAI11562.1).
• Expression System: HEK293
• Expression Region: Ala 39 - Lys 527
• Endotoxins: 1.0 EU per μg
• NCBI: AAI11562.1
• Storage: -20°C
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: LRRC4,NGL-2,BAG,NAG14
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.8 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human LRRC4 protein