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Catalog Number | orb107753 |
---|---|
Category | Proteins |
Description | Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells. IL-9 wasoriginally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I (HTLVI)transformed T cell line. It functions through the IL-9 receptor, which activates different signal transducer and activator (STAT)proteins and thus connects this cytokine to various biological processes. IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells. Human IL-9 has approximately 56 % amino acid sequence identity with murine IL-9. The geneencoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthmademonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness |
Tested applications | HPLC, SDS-PAGE |
Purity | > 95 % by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 14.1 kDa |
Target | IL-9 |
Protein Sequence | QGCPTLAGIL DINFLINKMQ EDPASKCHCS ANVTSCLCLG IPSDNCTRPC FSERLSQMTNTTMQTRYPLI FSRVKKSVEV LKNNKCPYFS CEQPCNQTTA GNALTFLKSL LEIFQKEKMRGMRGKI |
Biological Origin | E.coli |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4. |
Alternative names | Human Interleukin-9 protein Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human IL-9 protein
> 95% as determined by SDS-PAGE and HPLC. | |
14.1 kDa | |
E.Coli |
Unconjugated | |
90% | |
16.0 kDa | |
Human IL-9, His Tag (orb1184783) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Ile 144 (Accession # P15248-1). |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide. The apparent molecular mass of IL9-hFc is approximately 35-70 kDa due to glycosylation. | |
Mammalian |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 14.9 kDa after removal of the signal peptide. The apparent molecular mass of IL9-His is approximately 25-55 kDa due to glycosylation. | |
Mammalian |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 40.0 kDa after removal of the signal peptide. | |
Mammalian |