Human IL-7 R alpha / CD127 Protein

• Catalog Number: orb1496263
• Category: Proteins
• Description: Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 51.8 kDa
• Target: IL-7 R alpha
• Source: Human IL-7 R alpha, Fc Tag (orb1496263) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 (Accession # P16871-1).
• Expression System: HEK293
• Biological Activity: Immobilized Human IL-7 Protein at 2 μg/mL (100 μL/well) can bind Human IL-7 R alpha, Fc Tag with a linear range of 0.004-0.125 μg/mL (QC tested).
• Expression Region: Glu 21 - Asp 239
• Endotoxins: 1.0 EU per μg
• NCBI: NP_002176.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: IL7Ra,CD127
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.8 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Human IL-7 Protein at 2 μg/mL (100 μL/well) can bind Human IL-7 R alpha, Fc Tag (Cat. No. orb1496263) with a linear range of 0.004-0.125 μg/mL (QC tested).