Human IL-34 Protein

• Catalog Number: orb762403
• Category: Proteins
• Description: nterleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells.This entry represents interleukin-34 (IL-34), it was identified via functional screening of a library of secreted proteins [1]. This cytokine promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R)
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 27.3 kDa
• Target: IL-34
• Source: Human IL-34, His Tag (orb762403) is expressed from human 293 cells (HEK293). It contains AA Asn 21 - Pro 242 (Accession # Q6ZMJ4-1).
• Expression System: HEK293
• Biological Activity: Immobilized Human M-CSF R, Mouse IgG2a Fc Tag (MALS verified)at 5 μg/mL (100 μL/well) can bind Human IL-34, His Tag with a linear range of 0.4-2 ng/mL (QC tested).
• Expression Region: Asn 21 - Pro 242
• Endotoxins: 1.0 EU per μg
• NCBI: NP_689669.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, 0.2 M Arginine, pH7.4
• Alternative names: IL34,C16orf77,IL-34,Interleukin-34,MGC34647
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.3 kDa. The protein migrates as 32 kDa and 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Human M-CSF R, Mouse IgG2a Fc Tag (MALS verified) at 5 μg/mL (100 μL/well) can bind Human IL-34, His Tag (Cat. No. orb762403) with a linear range of 0.4-2 ng/mL (QC tested).